Ciwon sankarar lymphoblastic mai tsanani (T-ALL)-05

Gyaran Marasa Lafiyar T-ALL Mai Lalacewa Da Ciwon Jijiyoyin Tsakiyar Jijiyoyi Bayan Maganin CAR-T

Wannan lamari ya shafi wani yaro ɗan shekara 16 daga Arewa maso Gabashin China, wanda tafiyarsa da cutar sankarar jini ta cika da ƙalubale tun bayan gano cutar a cikin shekara guda da ta gabata.

A ranar 8 ga Nuwamba, 2020, Dawei (wani sunan barkwanci) ya ziyarci wani asibiti na yankin saboda taurin fuska, kuraje, da kuma bakin da ya karkace. An gano yana da "cutar sankarar lymphoblastic mai tsanani (nau'in ƙwayoyin T)." Bayan wani kwas na maganin chemotherapy na induction, MRD (ƙaramin cutar da ta rage) ba ta da cutar, sai kuma maganin chemotherapy na yau da kullun. A wannan lokacin, huda ƙashi, huda ƙashi, da allurar ciki ba su nuna wata matsala ba.

A ranar 6 ga Mayu, 2021, an yi huda a lumbar tare da allurar intrathecal, kuma binciken ruwan cerebrospinal (CSF) ya tabbatar da "leukemia na tsarin jijiyoyi na tsakiya." Bayan haka, an yi amfani da nau'i biyu na chemotherapy akai-akai. A ranar 1 ga Yuni, an yi huda a lumbar tare da nazarin CSF ya nuna ƙwayoyin da ba su kai ba. An yi ƙarin huda a lumbar guda uku tare da allurar intrathecal, inda gwajin ƙarshe na CSF bai nuna ƙwayoyin ƙari ba.

A ranar 7 ga Yuli, Dawei ya fuskanci matsalar gani a idonsa na dama, wanda ya ragu zuwa haske kawai. Bayan wani gwaji na musamman na maganin chemotherapy, hangen idonsa na dama ya koma daidai.

A ranar 5 ga Agusta, ganin idonsa na dama ya sake tabarbarewa, wanda hakan ya haifar da makanta gaba ɗaya, kuma idonsa na hagu ya yi duhu. Daga 10 zuwa 13 ga Agusta, an yi masa aikin radiotherapy na kwakwalwa da kashin baya (TBI), wanda ya dawo masa da gani a idonsa na hagu, amma idonsa na dama ya kasance makaho. A ranar 16 ga Agusta, an yi gwajin MRI na kwakwalwa ya nuna ɗan ci gaba a cikin kauri na jijiyar gani ta dama da kuma chiasm, tare da lura da ƙarin girma. Ba a sami wata alama ko ƙarin ci gaba ba a cikin parenchyma na kwakwalwa.

A wannan lokacin, iyalin sun shirya don dashen ƙashi, suna jiran gado kawai a sashen dashen. Abin takaici, gwaje-gwajen da aka yi kafin dashen sun nuna matsalolin da suka sa dashen ba zai yiwu ba.