ʻO ka maʻi ʻaʻai māmā ʻaʻole liʻiliʻi (NSCLC)-02

Ua hōʻike mua ʻia kekahi maʻi kāne 82 makahiki i ka hoʻomaka o Malaki 2023 me ka nāwaliwali ākea e holomua ana, ka nalowale o ka makemake, a me ka pohō kaumaha ma kahi o 5 kilokani. I ka wā i komo ai, ua hana ʻia nā hoʻokolohua kikoʻī. Ua hōʻike ʻia kahi scan CT umauma i nā nodules he nui ma nā māmā ʻelua, ʻo ka nui loa ma kahi o 2.5 cm. ʻO ka nodule nui loa ma ka ʻāpana apical o ka lobe ʻākau haʻahaʻa a me ka nodule nui loa ma ka ʻāpana dorsal o ka lobe hema luna ʻelua he mau palena ʻike ʻole ʻia. Ma hope o ka biopsy umauma a me ka hoʻokolokolo pathological, ua hōʻoia ʻia ka maʻi ʻaʻai māmā non-small cell (NSCLC), me ka adenocarcinoma i loaʻa ma ka ʻāpana dorsal o ka lobe hema luna a me ka ʻāpana apical o ka lobe ʻākau haʻahaʻa.

Ma hope mai, ua loaʻa i ka mea maʻi kahi regimen immunotherapy NK cell. Ma hope o ka mahina mua o ka lāʻau lapaʻau, ʻaʻole i hōʻike kahi hoʻokolokolo hahai i kahi loli koʻikoʻi i ka nui o nā nodules māmā, akā ua hoʻomaikaʻi ʻia nā hōʻailona holoʻokoʻa o ka mea maʻi, me ka nāwaliwali i emi iho a me ka hoʻi mālie ʻana o ka makemake. Ma hope o ka lua o ka mahina o ka lāʻau lapaʻau, ua hōʻike kekahi scan CT umauma i kahi palena ʻoi aku ka maopopo a me ka emi iki ʻana o ka nui o ka nodule ma ka ʻāpana apical o ka lobe ʻākau haʻahaʻa, a me ka necrosis hapa me kahi outline i wehewehe ʻia o ka nodule ma ka ʻāpana dorsal o ka lobe hema luna. Ma hope o ke kolu o ka mahina o ka lāʻau lapaʻau, ua hōʻike ka CT umauma i ka emi hou ʻana o ka nui o nā nodules ma nā māmā ʻelua, me ka nodule nui loa i kēia manawa ʻaʻole i ʻoi aku ma mua o 1.5 cm, kahi omo ʻana o nā lesions pulmonary, a me ka hoʻomaikaʻi ʻana i ke olakino.

I ka hōʻuluʻulu manaʻo, ua hōʻike ka immunotherapy NK cell i ka pono maikaʻi a me ka hoʻomanawanui i kēia maʻi kāne 82 makahiki me NSCLC, me ka emi nui ʻana o nā ʻeha o ka māmā a me ka hoʻomaikaʻi nui ʻana i ke kūlana holoʻokoʻa o ka mea maʻi. E hoʻomau nā hoʻolālā mālama a me nā hoʻolālā lapaʻau hou aʻe e nānā i ka holomua o ka maʻi a me nā hopena lapaʻau.