Ka pae maʻi ʻaʻai Endometrial IVB-04

He wahine 55 makahiki ka mea maʻi, a ua hōʻoia ka histopathology o ka biopsy i ka maʻi ʻaʻai endometrial i hoʻokaʻawale ʻole ʻia ma ke kahua IVB.

Haʻahaʻa ka hoʻokaʻawale ʻana a kiʻekiʻe ka maʻi ʻino. Ua hoʻopili ʻia kāna puʻupuʻu a ʻaʻole hiki ke wehe loa ʻia e ke ʻoki kino. Ua hōʻike hou ka loiloi hou ʻana ua emi ka nui a me ka helu o nā lymphocyte i nā maʻi a me ka hana haʻahaʻa loa o nā cell NK. ʻAʻole hiki iā ia ke ʻae i nā hopena maikaʻi ʻole, ua haʻalele ʻo ia i ka chemotherapy a ua komo i kahi hoʻokolohua lapaʻau o nā cell NK koko kaula.

Ua loaʻa i kēia mea maʻi ka lāʻau lapaʻau mua i Pepeluali 2021 a ʻo ka lua o ka manawa i 6 mau mahina ma hope. No 4 mau lā i ka lālani, ua hana ʻia hoʻokahi intravenous infusion a me ka immunophenotyping i kēlā me kēia lā ma mua a ma hope o kēlā me kēia pōʻai o ka lāʻau lapaʻau.

Ma hope o ka papa hana mua o ka immunotherapy i loko o nā pūnaewele NK koko kaula, ua hoʻopau hapa ka mea maʻi. Ua hoʻomaikaʻi ʻia kona ikaika kino, kona makemake, a me kona ʻano hiamoe.

Ma hope o ka lua o ka papa hana, ua hana ka mea noiʻi i kahi scan PET-CT. Ua hōʻike ka scan i ka emi ʻana o ka nui o ka nui hypermetabolic o ka ʻōpū ʻākau a me ka emi nui ʻana o ka metabolism a me ka nui o ka ʻōpū i hoʻohālikelike ʻia me ka wā ma mua o ka mālama ʻana. ʻOiai ʻaʻole i loli ka nui o ke poʻo femoral ʻākau a me ka metastasis o ka iwi ʻākau 10 a me 11, ua maʻamau ka metabolism o nā metastases iwi. Ua nalowale pū nā metastases o ka lymph node he nui ma ka ʻāʻī, mediastinum, retroperitoneum, a me ka pelvis.

Ma hope o ʻelua mau papa, ua emi ke kūlana kino mai 3 a i 1 a ua hoʻomaikaʻi nui ʻia ke ʻano o ke ola.