Gawo la khansa ya endometrial IVB-04

Wodwalayo anali mkazi wazaka 55, ndipo histopathology ya biopsy inatsimikizira kuti ali ndi khansa ya endometrial IVB yomwe sinasiyanitsidwe bwino.

Kusiyanitsa kochepa komanso khansa yayikulu. Chotupa chake chinali chitafalikira ndipo sichingathe kuchotsedwa kwathunthu ndi opaleshoni. Kuwunika kwina kunawonetsa kuti odwalawo anali ndi kuchuluka kwa ma lymphocyte komanso kuchuluka kwa maselo a NK komwe kunali kochepa kwambiri. Polephera kupirira zotsatirapo zoyipa, anasiya mankhwala a chemotherapy ndipo anatenga nawo mbali mu mayeso azachipatala a maselo a NK a magazi a chingwe.

Wodwalayu adalandira chithandizo choyamba mu February 2021 ndipo kachiwiri analandira chithandizocho patatha miyezi 6. Kwa masiku anayi otsatizana, kulowetsedwa kamodzi patsiku m'mitsempha ndi immunophenotyping kunachitika asanayambe komanso pambuyo pa chithandizo chilichonse.

Pambuyo pa chithandizo choyamba cha immunotherapy m'maselo a NK a magazi a chingwe, wodwalayo anachira pang'ono. Mphamvu zake zakuthupi, chilakolako chake, komanso kugona kwake kunali kutakwera.

Pambuyo pa chithandizo chachiwiri, wofufuzayo adachita PET-CT scan. Kujambulako kunawonetsa kuchepa kwa kukula kwa hypermetabolic mass ya chiberekero choyenera komanso kuchepa kwakukulu kwa kagayidwe kachakudya ndi kuchuluka kwa chiberekero poyerekeza ndi chithandizo chisanachitike. Ngakhale kuti mutu wa femoral woyenera ndi metastasis ya nthiti ya 10 ndi 11 yoyenera sizinasinthe, kagayidwe ka metastases ya mafupa kanali kabwinobwino. Metastases ya ma lymph node ambiri m'khosi, mediastinum, retroperitoneum, ndi pelvis zinathanso.

Pambuyo pa maphunziro awiri, chiwerengero cha thupi chinachepa kuchoka pa 3 kufika pa 1 ndipo moyo unasintha kwambiri.