Iindaba zeNkampani

Uphononongo oluphambili lubonisa ukusebenza okumangalisayo konyango lweeseli ze-CAR-T ekunyangeni i-B-cell Acute Lymphoblastic Leukemia (B-ALL). Olu phando, olubandakanya intsebenziswano ne-BIOOCUS kunye neSibhedlele saseLu Daopei, lubonisa inkqubela phambili ebalulekileyo, lumisela unyango njengokhetho olubalulekileyo lonyango.

Abaphandi abavela kwiSibhedlele iLu Daopei kunye nabasebenzi bamanye amazwe bahlola unyango lweeseli zeCAR-T oluphambili, olunika ithemba kwizigulana ezine-B cell monicancies. Olu phononongo lubonisa inkqubela phambili kuyilo kunye nokusetyenziswa, lubonisa iziphumo ezithembisayo kunye namathuba okuvelisa izinto ezintsha kwixesha elizayo.

Izifundo zeklinikhi zakutshanje zityhila ukuba iiseli ze-CD19 CAR-T ezisekelwe kwi-4-1BB zibonisa ukusebenza kakuhle kakhulu ekulweni nethumba xa kuthelekiswa neeseli ze-CAR-T ezisekelwe kwi-CD28 ekunyangeni i-B cell ephinde yabuyela kwi-relaxation okanye enganyangekiyo (r/r B-ALL).

Uphononongo lwakutshanje kwiSibhedlele iLu Daopei lubonise ukusebenza kakuhle kunye nokhuseleko oluphezulu lwe-CD19 CAR-T cell therapy yedosi ephantsi ekunyangeni izigulane ze-B acute lymphoblastic leukemia (B-ALL) eziphinde zagula okanye eziphinde zagula. Olu phando, oluquka izigulane ezingama-51, lubonise izinga elimangalisayo lokuxolelwa ngokupheleleyo kunye neziphumo ebezingalindelekanga ezincinci.

Isibhedlele iLu Daopei kunye neHebei Senlang Biotechnology zibhengeze iziphumo ezithembisayo ezivela kuphando lwazo lwakutshanje malunga nokhuseleko kunye nokusebenza kakuhle konyango lwe-CAR-T kwi-acute B cell leukemia. Le ntsebenziswano igxininisa amandla oyilo olutsha lweeseli ze-CAR-T ukuphucula iziphumo zesigulana.

Uphononongo olutsha olukhokelwa nguGqr. Zhi-tao Ying wasePeking University Cancer Hospital lubonise ukhuseleko kunye nokusebenza kakuhle konyango lweeseli ze-IM19 CAR-T ekunyangeni umhlaza we-B-cell obuyela umva kunye nongasasebenziyo. Ipapashwe kwi Ijenali yaseTshayina yeZiyobisi eziNtsha, olu phononongo luxela ukuba izigulane ezili-11 kwezili-12 zifumene ukuphumla ngokupheleleyo ngaphandle kwemiphumo emibi kakhulu, nto leyo ebonisa amandla e-IM19 njengonyango oluthembisayo kwizigulane ezinezinye iindlela ezinqongopheleyo.

UQeqesho lwaminyaka le luka-2024 loLawulo lweGazi lweKliniki kunye neTekhnoloji yoTyalelo lwegazi eSanhe City lubanjwe ngempumelelo kwiSibhedlele iYanda Ludaopei. Lo msitho ujolise ekuphuculeni ulawulo lwegazi lweklinikhi kunye nokhuseleko lotofelo-gazi ngeeseshoni zoqeqesho ezibanzi ezizinyaswe ziingcali zempilo ezingaphezu kwe-100 ezivela kumaziko ezonyango ahlukeneyo.

Ukuqinisekisa amava onyango olukhuselekileyo nolukhululekileyo kwizigulane ezine-leukemia kubandakanya ukhathalelo olucokisekileyo lwemihla ngemihla, kubandakanya ucoceko lokusingqongileyo, ucoceko lomntu, ukutya okunempilo, kunye nokuzilolonga okufanelekileyo. Esi sikhokelo sinika iingcebiso ezibalulekileyo zokhathalelo olusebenzayo lwemihla ngemihla ukuxhasa ukuchacha.

Uphononongo lwakutshanje lubonisa ukusebenza kakuhle kunye nokhuseleko lwe-NS7CAR-T cell therapy ekunyangeni i-T-cell acute lymphoblastic leukemia (R/R T-ALL) ephinde yabuyela kwi-relaxation okanye i-refractory okanye i-refractory T-cell lymphoblastic lymphoma (R/R T-LBL). Olu nyango lunika ithemba elitsha kwizigulane ezinezi ntlobo zomhlaza eziqatha.

I-12th Annual Lu Daopei Hematology Forum imiselwe ukuba ibanjwe nge-23-24 ka-Agasti 2024, kwiZiko leeNgqungquthela zaMazwe ngaMazwe laseBeijing. Joyina nathi kwiingxoxo ezinolwazi kunye nophuhliso lwamva nje kwi-hematology.

Uphononongo lweklinikhi lwesigaba soku-1 lwe-CD7 CAR-T ye-R/R AML lwenziwa liqela likaDaopei Lu kwi-ASHIntlanganiso yoNyaka yama-65 ye-American Society of Hematology (ASH) ibanjelwe ngaphandle kwe-intanethi (eSan Diego, e-USA) nakwi-intanethi ngoDisemba 9-12, 2023. Iingcali zethu zenze umboniso omhle ngale ntsebenziswano...

I-American Society of Hematology (ASH) yeyona ntlanganiso iphambili yezemfundo kwicandelo le-hematology kwihlabathi liphela. Inyani yokuba iSibhedlele iLu Daopei sikhethwe njengesokugqibela kwi-ASH iminyaka ilandelelana ibonisa ngokupheleleyo impumelelo yaso kwezemfundo kwi...