Ngā Pūrongo Kamupene

E whakaatu ana tētahi rangahau hou i te whai huatanga whakamiharo o te rongoā pūtau CAR-T ki te rongoā i te mate Leukemia Lymphoblastic Acute pūtau-B (B-ALL). Ko te rangahau, e uru ana ki te mahi tahi me BIOOCUS me te Hōhipera o Lu Daopei, e whakaatu ana i ngā whanaketanga nui, e whakatū ana i te rongoā hei kōwhiringa maimoatanga nui.

Kei te tūhuratia e ngā kairangahau o te Hōhipera o Lu Daopei me ngā hoa mahi o te ao ngā maimoatanga pūtau CAR-T hou, e tuku ana i te tumanako ki ngā tūroro he mate pukupuku pūtau-B. E whakaatu ana tēnei rangahau i ngā whanaketanga o te hoahoa me te tono, e whakaatu ana i ngā hua whai hua me te pūmanawa mō ngā auahatanga ā muri ake nei.

E whakaatu ana ngā rangahau haumanu tata nei he pai ake te whai huatanga o ngā pūtau CD19 CAR-T e ahu mai ana i te 4-1BB ki te rongoā i te leukemia lymphoblastic acute o ngā pūtau B kua hoki mai, kua uaua rānei te rongoā (r/r B-ALL) ki te whakataurite ki ngā pūtau CAR-T e ahu mai ana i te CD28.

I whakaatuhia e tētahi rangahau tata nei i te Hōhipera o Lu Daopei te whai huatanga me te haumaru o te rongoā pūtau CD19 CAR-T iti-horopeta ki te rongoā i ngā tūroro B acute lymphoblastic leukemia (B-ALL) uaua, kua hoki anō rānei ki te mate. I whakaatuhia e te rangahau, i uru atu ki te 51 ngā tūroro, he tere whakamīharo te murunga katoa me te iti o ngā pānga taha.

Kua whakapuakina e te Hōhipera o Lu Daopei me te Hebei Senlang Biotechnology ngā kitenga whakamīharo mai i tā rāua rangahau tata nei mō te haumaru me te whai huatanga o te rongoā CAR-T mō te mate pukupuku toto pūtau-B whakapeka. E whakaatu ana tēnei mahi tahi i te kaha o ngā hoahoa pūtau CAR-T hou ki te whakarei ake i ngā putanga o ngā tūroro.

Kua whakaatuhia e tētahi rangahau hou i arahina e Tākuta Zhi-tao Ying o te Peking University Cancer Hospital te haumaru me te whai huatanga o te rongoā pūtau IM19 CAR-T ki te rongoā i ngā mate pukupuku toto pūtau-B kua hoki mai me ngā mate pukupuku toto uaua. I whakaputaina ki te Te Puka Hainamana mō ngā Tarukino Hou, e ai ki te rangahau 11 o roto i te 12 ngā tūroro i ora katoa me te kore he pānga kino kino, e whakaatu ana i te kaha o te IM19 hei kōwhiringa maimoatanga whai hua mō ngā tūroro he iti noa ngā huarahi kē atu.

I tū angitu te Whakangungu ā-Tau 2024 mō te Whakahaere Toto Haumanu me te Hangarau Whakawhiti Toto i te Tāone o Sanhe i te Hōhipera o Yanda Ludaopei. Ko te whāinga o tēnei huihuinga he whakarei ake i te whakahaere toto haumanu me te haumaru o te whakawhiti toto mā roto i ngā wā whakangungu whānui i tae atu ai neke atu i te 100 ngā tohunga hauora mai i ngā whare hauora maha.

Ko te whakarite i tētahi wheako maimoatanga haumaru, whakamarie hoki mō ngā tūroro leukemia me whai wāhi ki te tiaki i ia rā, tae atu ki te akuaku taiao, te akuaku whaiaro, te kai totika, me te whakakori tinana tika. Kei roto i tēnei aratohu ngā tohutohu nui mō te tiaki whai hua o ia rā hei tautoko i te whakaora.

E whakaatu ana tētahi rangahau hou i te whai huatanga me te haumaru o te rongoā pūtau NS7CAR-T ki te rongoā i te mate pukupuku toto nui pūtau-T kua hoki mai, kua ātete rānei ki te mate pukupuku toto nui pūtau-T (R/R T-ALL) me te mate pukupuku toto nui pūtau-T (R/R T-LBL). Ka tukuna e tēnei rongoā he tumanako hou mō ngā tūroro e pāngia ana e ēnei momo mate pukupuku kaha.

Ka tū te Huihuinga Tau 12 o Lu Daopei Hematology i te 23-24 o Ākuhata, 2024, i te Beijing International Convention Center. Hono mai ki a mātou mō ngā kōrero whai kiko me ngā whanaketanga hou o te ao hematology.

I tū te wāhanga tuatahi o te rangahau haumanu o te CD7 CAR-T mō te R/R AML e te tīma a Daopei Lu ki te ASH. I tū te Hui-ā-Tau 65 o te American Society of Hematology (ASH) i waho o te ipurangi (San Diego, USA) me te ipurangi i te Hakihea 9-12, 2023. I whakaatu pai ā mātou tohunga i tēnei mahi tahi...

Ko te American Society of Hematology (ASH) te hui mātauranga matua o te ao mō te hematology. Ko te mea kua tohua te Hōhipera o Lu Daopei hei kaitono whakamutunga mō te ASH mō ngā tau karapīpiti e whakaatu ana i ana whakatutukitanga mātauranga i roto i te f...