Kugonjetsa Lymphoma ndi Chithandizo Chachiwiri cha CAR-T

Mayi wazaka 61, yemwe adalandira chithandizo chamankhwala ambiri a matenda a shuga B-Cell Lymphoma, kuphatikizapo maulendo asanu ndi awiri a chemotherapy, chithandizo cha CAR-T, ndi maulendo angapo a PD-1 kuphatikiza chemotherapy ndi radiation, adapezeka kuti ali pamavuto. Ngakhale kuti adayesetsa, vuto lake silinasinthe kwenikweni mpaka atafika ku BIOOCUS kuti akalandire chithandizo chapadera.

Kumayambiriro kwa chaka cha 2021, pamene lymphoma yake ikupita patsogolo mofulumira komanso kuyambitsa zilonda zoopsa pakhungu ndi kutupa, mkhalidwe wa wodwalayo unkaoneka woipa kwambiri. Motsogozedwa ndi gulu lodzipereka ku BIOOCUS, adayamba ulendo watsopano wochizira. Pambuyo pa chithandizo choyamba, vuto lake linakhazikika, zomwe zinapangitsa kuti ma lymphocyte ake asonkhanitsidwe ndi kukulitsidwa kuti agwiritsidwe ntchito pochiza maselo a CD19/CD22 CAR-T.

Pa February 19, 2021, adalandira chithandizo cha ma cell awiri a CAR-T. Ngakhale kuti adakumana ndi zotsatirapo zoyipa zomwe angathe kuzithetsa, ma PET-CT scan omwe adachitika pambuyo pake adawonetsa kusintha kwakukulu. Pofika mu Marichi, adapeza mpumulo wokwanira, zomwe zidasintha kwambiri pankhondo yake yolimbana ndi khansa.

Tsopano, patatha zaka zitatu kuchokera pamene adalandira chithandizo cha CAR-T, akugawana nkhani yake yochira ku Fourth Lymphoma ya ku China Msonkhano wa Odwala, wolimbikitsa ena omwe akukumana ndi mavuto ofanana. Ulendo wake ukugogomezera kupita patsogolo kwa mankhwala a CAR-T komanso udindo wofunikira wa mankhwala opangidwa payekha pochiza matenda ovuta a lymphoma.

Chifukwa cha chisamaliro chokwanira ku BIOOCUS, akupitilizabe kukula bwino, akugogomezera kufunika kwa njira zatsopano zochiritsira komanso thandizo la akatswiri odzipereka azaumoyo pothana ndi khansa.