Indwara ya Systemic Lupus Erythematosus (SLE)-01

Xiaohuan w'imyaka 24 amaze imyaka itatu yiga ubuganga muri kaminuza kandi amaze imyaka igera ku 10 arwaye indwara ya lupus erythematosus (SLE). Xiaohuan yagize ati: "Napimwe mfite imyaka 10, kandi muganga yavuze ko bigoye cyane kuyivura, ko nayigenzura gusa nkoresheje imiti." Mu myaka icumi ishize, yagombaga kujya kwisuzumisha buri kwezi no guhabwa imiti, kandi yavuwe imisemburo, avurwa n'ubudahangarwa bw'umubiri, ndetse anavurwa n'ibinyabuzima, ariko nta na kimwe cyamufashije. Yahuye n'ihungabana rikomeye, arwara uduheri twinshi, akagira umuriro mwinshi kandi ababara cyane.

Nyuma y’ibizamini bitandukanye by’ibanze, Xiaohuan yujuje ibisabwa byose byo kuvura CAR-T kuri SLE. Itsinda ry’inzobere ryateguye neza gahunda yo kuvura hashingiwe ku ndwara ye kandi ryiteguye neza inzira yo gukusanya uturemangingo. Ku ya 28 Werurwe, nibwo hatangiye gukusanya uturemangingo tw’ingirabuzimafatizo. Ku ya 22 Mata, yatangiye gukoresha imiti igabanya ubukana bw’uturemangingo. Ku ya 28 Mata, uturemangingo twongeye gushyirwamo. Uturemangingo twa T miliyoni makumyabiri twahinduwe na CAR twongewe buhoro buhoro mu mitsi ya Xiaohuan, twibasira uturemangingo twa lupus B, dutangira kurwana "n’igitero nyacyo, tuvune umwe umwe".

Ku itariki ya 4 Kamena, umunsi wa 38 nyuma yo guterwa inshinge, Xiaohuan yasubiye mu bitaro kugira ngo akurikiranwe. Ibisubizo by'isuzuma byagaragaje ko ibimenyetso byose by'ingenzi byari byagabanutse ku rugero rusanzwe. Xiaohuan yagize ati: "Sinkikeneye imiti igabanya imisemburo; numva ubuzima butangiye."