Intambara ya Wu: Kurwara indwara ya myeloma nyinshi

Umurwayi Wu, umugabo w'imyaka 71, yasanzwemo indwara ya myeloma nyinshi.

Yagiye kuvurirwa muri Bioocus International Medical Center mu 2022 kandi yashimishijwe cyane n'ubuvuzi bwe. Indwara ya mbere yagaragaje ibyavuye mu bushakashatsi bwa MRI yo mu ruhu na T5T, harimo kuvunika kwa T10, T11, na L1 cone hamwe no kubyimba kw'umusemburo w'amagufwa. Byongeye kandi, ibimenyetso bito bidasanzwe byagaragaye mu mubiri wa L2 vertebrae. Isuzuma ryakozwe ku gupfunyika kw'umusemburo w'amagufwa ryemeje myeloma y'uturemangingo twa plasma. Isuzuma ryinyongera ryagaragaje ko plasma ya prokaryotic igizwe na 46% by'umusemburo w'amagufwa, hamwe n'uturemangingo tudasanzwe twashyizwemo tugize 14% muri flow cytometry. Isuzuma ryakozwe ku magufwa ryagaragaje ko 70% bya problastoma. Isesengura rya FISH ryagaragaje ko gene yatakaye muri lq21 (CKSIB) na 1m32 (CDKN2C), mu gihe ikizamini cya FTSH cyagaragaje ko hari p53 gene yakuweho, naho ICH ntiyagaragaye ko ari mbi mu ikizamini cya FISH. Isuzuma rya nyuma ryagaragaje ko hari multiple osteoblastic follipoma (ubwoko bwa L light chain), aho DS yashyizwe mu itsinda rya B, ISS yashyizwe mu cyiciro cya III, na RISS yashyizwe mu cyiciro cya II. Umurwayi Wu yashimiye ubuvuzi bwuzuye kandi bwihariye bwatanzwe n'ikigo cy'ubuvuzi.

Amateka y'ubuvuzi bwabanje:

Ibimenyetso bya myeloma nyinshi biratandukanye, harimo cyane cyane kubura amaraso, kubabara mu magufwa, kunanirwa kw'impyiko, kwandura, kuva amaraso, ibimenyetso by'imitsi, hypercalcemia, n'imyanda ya amyloid. Ibitaro byafashe uburyo bukomeye bwo kuvura indwara no gukosora amaraso make n'udukoko duto tw'amaraso. Nyuma y'amezi agera kuri 2 BCMA CAR-T selile itera, ibimenyetso by'umurwayi byasubiye mu buryo busanzwe, kandi imimerere ye yari iri mu nzira yo kugenzurwa. Ikigo Mpuzamahanga cy’Ubuvuzi cya Bioocus cyakomeje gukurikirana umurwayi kugira ngo kirebe ko ingaruka zo kuvura zikomeza kumera neza.