Wu txoj kev sib ntaus sib tua: Kev txom nyem los ntawm ntau yam mob myeloma

Tus neeg mob Wu, ib tug txiv neej muaj hnub nyoog 71 xyoo, tau kuaj pom tias muaj mob multiple myeloma.

Nws tau nrhiav kev kho mob ntawm Bioocus International Medical Center hauv xyoo 2022 thiab nws txaus siab heev rau nws txoj kev kho mob. Thawj qhov kev kuaj mob tau qhia txog kev kuaj mob MRI thiab T5T ntawm lub duav, suav nrog T10, T11, thiab L1 cone fractures nrog rau pob txha o. Tsis tas li ntawd, cov cim me me uas tsis zoo tau pom hauv lub cev L2 vertebral. Kev kuaj mob vertebral puncture biopsy tau lees paub tias muaj plasma cell myeloma. Kev kuaj ntxiv tau qhia tias muaj prokaryotic plasma uas muaj 46% ntawm cov pob txha pob txha biopsy, nrog rau cov hlwb tsis zoo uas muaj 14% hauv flow cytometry. Bone junction biopsy qhia tau tias muaj 70% problastoma. Kev tshuaj xyuas FISH tau qhia txog kev poob ntawm cov noob caj noob ces hauv lq21 (CKSIB) thiab 1m32 (CDKN2C), thaum qhov kev xeem FTSH zoo rau p53 gene deletion, thiab ICH tsis zoo hauv qhov kev xeem FISH. Qhov kev kuaj mob zaum kawg yog ntau osteoblastic follipoma (L light chain type), nrog DS staging hauv theem B pawg, ISS staging III, thiab RISS staging hauv theem II. Tus neeg mob Wu tau hais lus ua tsaug rau qhov kev kho mob uas muaj txhij txhua thiab raws li tus neeg mob xav tau los ntawm lub chaw kho mob.

Keeb kwm kev kho mob yav dhau los:

Cov tsos mob ntawm ntau yam myeloma muaj ntau yam, feem ntau suav nrog kev tsis muaj ntshav txaus, mob pob txha, tsis muaj zog raum, kis kab mob, los ntshav, cov tsos mob ntawm lub paj hlwb, hypercalcemia, thiab cov quav amyloid. Lub tsev kho mob tau ua kev kho mob tiv thaiv kev kis kab mob thiab kho qhov tsis muaj ntshav txaus thiab cov ntshav qis. Kwv yees li 2 lub hlis tom qab BCMA CAR-T cell infusion, tus neeg mob cov cim qhia maj mam rov qab mus rau qhov qub, thiab nws tus mob tau tswj hwm. Bioocus International Medical Center tau saib xyuas tus neeg mob tas li kom ntseeg tau tias muaj kev ruaj khov ntawm cov txiaj ntsig kho mob.