Iindaba
Ukubaluleka Kweklinikhi Kweebhendi Zeeprotheyini ze-Oligoclonal Emva Konyango lwe-BCMA CAR-T Kwizigulane Ezininzi ZeMyeloma
Uphononongo olujonga emva luvavanya ukwenzeka kunye neziphumo zee-oligoclonal protein bands (APB) kwizigulane ezine-relapse/refractory multiple myeloma (MM) ezinyangwe ngonyango lwe-LCAR-B38M CAR-T, lugxininisa ulwalamano lwazo neziphumo eziphuculweyo.
Ibali lesigulana: Ukusuka kwi-AML-M2 Diagnosis ukuya kwi-Wintern yaseYunivesithi – Uhambo lweminyaka emihlanu oluya ekuPhileni
Imfazwe yeminyaka emihlanu yesigulana esiselula esine-leukemia nxamnye ne-AML-M2, eyaphelela ekufakweni kwe-haploidentical stem cell kwiSibhedlele saseLu Daopei, ivula indlela yobomi bakhe obutsha njengomfundi waseyunivesithi.
Uphononongo lweMulti-Center lubonisa ukubikezela okuhle kwezigulana zeHematologic Malignancy ezifakelwa i-MMUD Allogeneic Stem Cell Transplant nge-ATG
Uphononongo olukhulu oluqhutywa ngamaziko amaninzi eTshayina lubonisa iziphumo ezilungileyo kwizigulana ezine-hematologic malignancies ezifakelwa iiseli ze-stem cell ezingafaniyo (MMUD) nge-ATG yokuthintela i-GVHD.
Ibali lesigulana: I-B-ALL enobungozi obukhulu, ukufakelwa kweBone Marrow kwiinyanga ezili-9, kwiminyaka emibini kamva—isiqalo esisempilweni somlwi oselula
Umntwana oneenyanga ezili-9 ubudala, ofunyaniswe ene-Acute B Lymphoblastic Leukemia (B-ALL) enobungozi obuphezulu, utyando lwe-bone marrow oluphumeleleyo. Emva kweminyaka emibini, umntwana ukhula kakuhle kwaye ulungele ukuya kwisikolo sabantwana abancinci.
Ukukhawulezisa Ukulungiswa Kweeseli ze-CAR-T Ukuphucula Iziphumo Zezigulane
Uphononongo lwakutshanje kwi I-Lancet Haematology igxininisa inkqubela phambili entsha kunyango lweeseli zeCAR-T, igxile ekuphuculeni isantya semveliso, ukuphucula ukusebenza kakuhle konyango, kunye nokwandisa ukufikelela kwizigulana ezinegazi kunye neethumba eziqinileyo.
Unyango lweBrexu-cel CAR-T lubonisa iziphumo ezithembisayo kwizigulane zabantu abadala ezisebenzisa i-R/R B-ALL
Uphononongo lwakutshanje kwi Ijenali ye-Clinical Oncology Ixela iziphumo ezilungileyo zonyango lwe-CD19 CAR-T i-brexucabtagene autoleucel (brexu-cel) ekunyangeni i-B-cell acute lymphoblastic leukemia (R/R B-ALL) ephinde yabuyela kwisimo sayo sokuqala/esingenakuphikiswa, inika ithemba lamazinga aphezulu okuxolelwa kunye nokusinda okuphuculweyo kwiimeko zokwenyani.
Ukuqonda iThalassemia: Isikhokelo esipheleleyo kwiifom zeAlfa kunye neBeta
I-Thalassemia sisifo esingaphezulu kwesinye. Esi sikhokelo sihlola zombini i-alpha kunye ne-beta thalassemia, izizathu zazo, iimpawu, kunye neendlela zonyango zamva nje ezifumaneka kwi-BIOOCUS International Medical Center.
Ukusuka Ekungakwazini Kwe-Graft Ekuqaleni Ukuya Ekubuyeleni Ngokupheleleyo: Uhambo Lwesigulana NgeProtokholi Yokufakelwa Kwesigulana Ephambili KaLu Daopei
Emva kokuxilongwa kwe-acute B-lymphoblastic leukemia kunye nokungaphumeleli kokuqala kokufakelwa, indlela yesigulana yokuchacha yayibonakala imbi. Nangona kunjalo, ngenxa yolwazi lweqela lezonyango likaLu Daopei kunye nokufakelwa okwesibini okuvela kumntu ongengowazalamane, ithemba nempilo zibuyile.
Ukusinda Xa Kunzima: Uhambo Lweminyaka Eli-14 Lokuqina Ekulweni NeMelanoma Yesigaba Sesine
UJennifer Ficko, owafunyaniswa ene-stage IV melanoma eneminyaka engama-48 ubudala, akazange ahlangabezane nazo zonke izinto ebezilindelwe. Ngonyango olumangalisayo olufana nonyango lwe-TIL kunye nenkxaso engagungqiyo yosapho lwakhe, uhlale engenaso isifo somhlaza kangangeminyaka engaphezu kwesixhenxe, ebhiyozela ukusinda kwakhe okumangalisayo kweminyaka eli-14.
Ukoyisa i-Leukemia: Uhambo lweNtombazana Encinci Lokunyamezela Nokuthemba kwiSibhedlele saseLu Daopei
Ngowama-2016, intombazana eneminyaka eli-11 ubudala, uWenwen (ogama lakhe lingu-alias), yafunyaniswa ukuba ine-acute T-cell lymphoblastic leukemia. Ejongene nemingeni esongela ubomi, yena nosapho lwakhe baphendukela kwiSibhedlele iLu Daopei ukuze bafumane unyango. Namhlanje, emva kokufakelwa utyando ngempumelelo neminyaka yokuchacha, uyaqhubeka nokulungiselela iimviwo zakhe zokungena eyunivesithi.
Unyango lweSeli ye-NK oludityaniswe ne-DC Vaccine lubonisa ukuphucuka okukhulu kumhlaza wesibindi okwinqanaba lokugqibela
Impumelelo enkulu kunyango lomhlaza wesibindi ophucukileyo ivele ngokudibanisa okutsha kwe-NK cell therapy, i-DC vaccine, kunye ne-Nivolumab. Olu nyango oludibeneyo lwe-immunotherapy lubonise impumelelo emangalisayo, nto leyo ekhokelele ekunciphiseni okukhulu kwethumba kunye nokuphucula ukusebenza kwesibindi kwiiveki ezintandathu kuphela kwisigulana esine-hepatocellular carcinoma esekwinqanaba lokugqibela.
UDkt. Lu Peihua Uveza Impumelelo kwi-CAR-T Therapy kwiNtlanganiso yoNyaka yama-29 ye-APBMT
KwiNtlanganiso yoNyaka yama-29 ye-Asia-Pacific Blood and Marrow Transplantation (APBMT), uGqr. Lu Peihua unike intetho ephambili malunga nempumelelo yonyango lweeseli ze-CAR-T eTshayina. Idatha yokwenyani yeqela lakhe evela kunyango lwezonyango yamkelwe kwihlabathi liphela, ibonisa igalelo labo kunyango lwezifo ezibangelwa ligazi.