Melanoma yemaziso (pakutanga), ichiteverwa nekenza yechiropa-02

Muna 2021, Mai Y vakangoerekana vaona chimwe chinhu chisina kujairika mukuona kweziso ravo rekurudyi. Kuongororwa kwakazara kwakaratidza kuti vaiva ne melanoma yemaziso. Nerombo rakanaka, yakaonekwa nekukurumidza uye yakarongwa sedanho rekutangaA, ine mukana we2% chete wekupararira kwemasero eropa. Mushure mekurapwa ne radiotherapy, vakanga vasina kenza kwenguva pfupi, kunyange zvazvo mari yacho yaive upofu hwechigarire muziso rakakanganiswa.

Zvisinei, zvinosuwisa kuti bundu iri rakadzoka gore rakatevera ndokutanga kukura nekukurumidza. Mifananidzo yakaratidza kuti chiropa chake chakanga chatova nemabundu anodarika gumi ane saizi dzakasiyana. Nekuda kweizvozvo, nyanzvi dzakamukurudzira kuti atore chikamu mukuyedzwa kwekiriniki kweTIL (tumor-infiltrating lymphocyte).

Baba vaMs. Y nemurume wavo vakaunganidza zvinyorwa zvavo zvekurapa ndokutaura navanachiremba munyika yese kuti vawane bvunzo yakakodzera yekiriniki, pakupedzisira vakawana chirongwa chedu. Nzira iyi inoshandisa masero emuviri ekudzivirira chirwere kurwisa kenza.

Vanachiremba vakabvisa chikamu chebundu kubva muchiropa chaMs. Y, vakabvisa masero eT anouraya kubva mariri, ndokuawedzera kusvika pamabhiriyoni gumi kusvika zana nemakumi mashanu, vachiumba uto remasero eclone. Uto guru iri remasero rakazodzorerwa mumuviri wake kuti ripe kurwisa kwakasimba, kwakasimba, uye kwenguva refu pamasero ekenza.

Kukura kwemasero eTIL kwakatora mavhiki matatu uye kwaida kurapwa kamwe chete. MunaGunyana 2023, Ms. Y vakapedza vhiki vachipiwa chemotherapy, TIL infusion, uye IL-2. Kurapwa uku kwakasimba kwakakonzera migumisiro yakaipa, kusanganisira kurwadziwa kwemajoini, kufema, zviratidzo zvemudumbu, mapundu, uye musoro wakanyanya.

Zvisinei, mushure mekunge migumisiro iyi yapera, chishamiso chakaitika. Kurapa kweTIL kwakaratidza kushanda zvakanaka. Mukati megore rimwe chete, bundu rese raMs. Y rakanga ranyangarika kana kuderera, zvichisiya rimwe chete. Muna 2024, vanachiremba vakabvisa inenge hafu yechiropa chake, kusanganisira bundu rekupedzisira. Paakamuka, akaudzwa kuti pakanga pasina zviratidzo zvechirwere mumuviri wake.