Te melanoma kanohi (i te tīmatanga), ā, muri iho ka horapa ngā pukupuku ate-02

I te tau 2021, ka kite ohorere a Whaea Y i tētahi āhua rerekē o te tirohanga o tōna kanohi matau. I kitea i roto i ngā whakamātautau whānui he mate pukupuku kanohi tōna. Waimarie, i kitea wawetia, ā, i whakarōpūtia hei wāhanga 1A, me te 2% noa iho o te tūponotanga ka horapa te mate. I muri i te whiwhinga i te rongoā irahiko, i kore ia e pangia e te mate pukupuku mō tētahi wā poto, ahakoa ko te utu he matapo tuturu i roto i te kanohi e pāngia ana.

Heoi, heoi anō, i te tau i muri mai ka hoki mai te pukupuku, ā, ka tere haere te tipu. I whakaatuhia e te whakaahua kua neke atu i te tekau ngā pukupuku o tōna ate, he rerekē te rahi. Nō reira, i tūtohu ngā tohunga kia uru atu ia ki tētahi whakamātautau haumanu TIL (tumor-infiltrating lymphocyte).

I kohia e te matua tāne a Whaea Y ana pūkete hauora, ā, i whakapā atu ki ngā tākuta puta noa i te motu kia kitea he whakamātautau haumanu e tika ana, ā, i te mutunga ka kitea tā mātou kaupapa. Ka whakamahia e tēnei tikanga ngā pūtau ārai mate o te tinana hei whawhai ki te mate pukupuku.

I tangohia e ngā tākuta tētahi wāhanga o te pukupuku mai i te ate o Whaea Y mā te pokanga, i wehea ngā pūtau-T whakamate mai i roto, ā, i whakawhanuitia kia tae ki te 10 ki te 150 piriona te maha, ka hangaia he ope pūtau tāruarua. Kātahi ka whakahokia mai tēnei ope pūtau nui ki roto i tōna tinana hei tuku i ngā whakaeke tika, kaha, me te pumau ki ngā pūtau matepukupuku.

E toru wiki te roa o te whakatipu i ngā pūtau TIL, ā, kotahi noa te wā maimoatanga i hiahiatia. I te marama o Hepetema 2023, i whai wāhi a Whaea Y ki te rongoā chemotherapy mō te wiki kotahi, ki te werohanga TIL, me te IL-2. Nā tēnei maimoatanga kaha i puta ai ngā pānga kino kino, tae atu ki te mamae o ngā hononga, te uaua o te manawa, ngā tohumate o te puku, te ponana, me te mamae o te upoko.

Heoi, i muri i te memeha haere o ēnei pānga taha, ka puta he merekara. I tino whai hua te rongoā TIL. I roto i te tau kotahi, tata katoa ngā pukupuku o Ms. Y kua ngaro, kua whakaiti rānei, kotahi anake te toenga. I te tau 2024, tata ki te haurua o tōna ate i tangohia e ngā tākuta, tae atu ki te pukupuku whakamutunga. I tōna oho ake, ka kīia ki a ia kāore he tohu mate e toe ana i roto i tōna tinana.