Melanoma ya m'maso (poyamba), kenako khansa ya chiwindi yomwe imafalikira m'matupi a anthu-02

Mu 2021, Mayi Y mwadzidzidzi adazindikira vuto la masomphenya a diso lake lamanja. Kufufuza kwathunthu kunawonetsa kuti anali ndi khansa ya m'maso. Mwamwayi, idapezeka msanga ndipo idayikidwa mu gawo 1A, ndi mwayi wokha wa 2% wa kufalikira kwa khansa. Atalandira chithandizo cha radiotherapy, analibe khansa kwakanthawi, ngakhale mtengo wake unali khungu losatha m'diso lomwe linakhudzidwa.

Komabe, mwatsoka, chotupacho chinabwereranso chaka chotsatira ndipo chinayamba kukula mofulumira. Zithunzi zinasonyeza kuti chiwindi chake chinali kale ndi zotupa zoposa khumi za kukula kosiyanasiyana. Chifukwa chake, akatswiri adamulangiza kuti achite nawo kafukufuku wa TIL (chotupa-cholowa m'thupi).

Bambo ndi mwamuna wa Ms. Y anasonkhanitsa zolemba zake zachipatala ndipo analankhulana ndi madokotala m'dziko lonselo kuti apeze mayeso oyenera azachipatala, ndipo pamapeto pake anapeza pulogalamu yathu. Njirayi imagwiritsa ntchito maselo a chitetezo cha mthupi kuti amenyane ndi khansa.

Madokotala anachotsa chotupacho m'chiwindi cha mayi Y, nachotsa maselo a T opha anthu ambiri, ndipo anachikulitsa kufika pa 10 mpaka 150 biliyoni, zomwe zinapanga gulu lankhondo la maselo a clone. Gulu lalikulu la maselo limeneli linabwezeretsedwanso m'thupi lake kuti lipereke ziwopsezo zenizeni, zamphamvu, komanso zopitilira pa maselo a khansa.

Kulima maselo a TIL kunatenga pafupifupi milungu itatu ndipo kunafunika chithandizo chimodzi chokha. Mu Seputembala 2023, Ms. Y adapatsidwa chithandizo cha chemotherapy kwa sabata imodzi, kulowetsedwa kwa TIL, ndi IL-2. Chithandizo champhamvuchi chinayambitsa zotsatirapo zoyipa, kuphatikizapo kupweteka kwa mafupa, kupuma movutikira, zizindikiro za m'mimba, ziphuphu, ndi mutu waukulu.

Komabe, pambuyo poti zotsatirapo zake zachepa, chozizwitsa chinachitika. Chithandizo cha TIL chinakhala chothandiza kwambiri. Pasanathe chaka chimodzi, pafupifupi zotupa zonse za Ms. Y zinatha kapena kuchepa, zomwe zinasiya chimodzi chokha. Mu 2024, madokotala anachotsa pafupifupi theka la chiwindi chake, kuphatikizapo chotupa chomaliza. Atadzuka, anauzidwa kuti panalibe zizindikiro za matenda m'thupi lake.