Umdlavuza wesibeletho-03

UNksz K, owesifazane oneminyaka engu-55 ubudala onesizinda esicebile ohlala phesheya kwezilwandle, wabhekana nomdlavuza ngokungazelelwe. Eminyakeni emithathu edlule, wazizwa engakhululekile futhi evuvukala esiswini sakhe esingezansi, okuhambisana nokuncipha kwesifiso sokudla. Lapho ehlolwa esibhedlela sangaphandle, kwatholakala ukuthi unomdlavuza wesibeletho wesigaba sesi-4. Ngenxa yesigaba esithuthukile kanye nezimila eziningi ezitholakale lapho kuvulwa isisu, ukususwa ngokuhlinzwa kwakungenakwenzeka, okwashiya i-chemotherapy njengenye indlela kuphela.

Ngemva kokuhlinzwa, uphawu lwesimila i-CA125 esegazini lakhe lwanda kusuka ku-1800 U/mL lwaya ngaphezu kuka-5000 U/mL. Ukwelashwa ngamakhemikhali okuqhubekayo kwabonisa ukusebenza okuncane kakhulu, kanti i-CA125 yanda futhi yaya ngaphezu kuka-8000 U/mL ezinyangeni eziyisithupha kamuva. Odokotela bazise umndeni wakhe ukuthi isikhathi sakhe esisele sasilinganiselwe futhi babeluleka ukuba balungiselele ngokwengqondo. Naphezu kokufunda ngobunzima besimo sakhe, uNksz K akazange abonise izimpawu zokuphelelwa yithemba. Ngaphambi kokulahla ithemba, wayefuna ukuzama ukwelashwa nge-immunotherapy.

Ngonyaka odlule, uNkk. K wahlinzwa okokuqala ukuze athathwe amasampula. Ngemva kwezinyanga ezimbili zokwandiswa kwe-ex vivo, ama-TIL aphinde afakwa emzimbeni wakhe. Waba nomkhuhlane ngosuku lokufakwa, owaphela ngosuku olulandelayo, futhi wazizwa engcono kakhulu. Manje, ngemva kwezinyanga eziyisithupha zokwelashwa, amazinga akhe e-CA125 ahlale engaphansi kuka-18 U/mL. Ukuqhathaniswa kwezithombe ze-PET-CT kubonisa ukuthi kuma-tumor okuqala angu-24 asakazeke emzimbeni wakhe, kusasele elilodwa kuphela. NgoMashi walo nyaka, uNkk. K wahlinzwa okwesibili ukuze athathwe amasampula.