Myasthenia gravis-01

Nyaya yekurapwa kweMyasthenia Gravis naZhang Wei

Zhang Wei, mainjiniya wesoftware ane makore makumi matatu nemaviri, akatanga kuona zviratidzo zve myasthenia gravis (MG) makore maviri apfuura. Pakutanga, aive ne ptosis (maziso akarembera) uye aisaona zvakanaka, asi zviratidzo zvake zvakawedzera nekufamba kwenguva, zvichikonzera kushaya simba kwetsandanyama izvo zvakakanganisa zvakanyanya basa rake nehupenyu hwake hwezuva nezuva. Pasinei nekurapwa kwakasiyana-siyana, kusanganisira mishonga ye anticholinesterase, immunosuppressants, uye intravenous immunoglobulin, zviratidzo zvake zvakaramba zviripo uye zvaiwanzo dzoka.

Nekurapa kwechivanhu kusina kushanda, vanachiremba vakakurudzira kuti Zhang Wei aedze nzira itsva yekurapa: CAR-T cell therapy. Kurapa uku kutsva kunoshandisa genetic engineering kugadzirisa T cells dzemurwere, zvichiita kuti dzikwanise kunanga nekubvisa masero asina kujairika ane chekuita nechirwere ichi.

Mushure mekuongororwa kwakazara, Zhang Wei akanzi akakodzera kurapwa. Vanachiremba vakatanga vabvisa masero eT mumuviri wake ndokuachinja majini ndokuawedzera murabhoritari. Zhang Wei akazopihwa chemotherapy yekudzivirira huwandu hwemalymphocytes aripo mumuviri wake, vachigadzirira kuunzwa kwemasero eCAR-T. Pakupedzisira, masero eCAR-T akagadziriswa akaiswazve mumuviri waZhang Wei.

Pakutanga kurapwa, Zhang Wei akanzwa kuneta kwenguva pfupi, asi mavhiki maviri gare gare, zviratidzo zvake zvakatanga kuvandudzika zvakanyanya. Kuora kwemaziso uye kuona zvisina kujeka zvakaderera zvakanyanya, uye simba rake rakadzoka zvishoma nezvishoma. Mwedzi mumwe chete gare gare, kushanda kwake nesimba kwakavandudzika, uye akakwanisa kutangazve mabasa ake ezuva nezuva. Mwedzi mitatu mushure mekurapwa, zviratidzo zvaZhang Wei zvakanga zvava kuda kunyangarika zvachose, uye akanga asisade mishonga yekare. Ongororo dzakatevera dzakaratidza kuti masoja ake emuviri akanga ari mumamiriro akanaka, pasina migumisiro yakaipa kana zviratidzo zvekudzokera kwechirwere.

Kuburikidza nekurapwa neCAR-T cell therapy, Zhang Wei's myasthenia gravis yakadzorwa zvakanyanya, zvichiwedzera hupenyu hwake uye kugona kwake kushanda. Kurapa uku kunopa tariro itsva kune varwere vazhinji vane myasthenia gravis.