Mukomana mudiki ane ushingi wekuRussia ari kurwisa neuroblastoma

Pane mukomana mudiki ane ushingi anonzi Lev Kovalev. Ane makore manomwe chete ekuberekwa, uye anobva kuRussia. Sei tichimuti akashinga? Heino nyaya yake inokurudzira.

Lev akaonekwa aine chirwere che neuroblastoma makore maviri apfuura, kenza yakaoma yakanga yakura pasinei nekurapwa kwekutanga. Mhuri yake yakashungurudzika pavakanzwa nezvekubatwa kwemupfupa wemapfupa nezvimwe zvinetso zvakaratidzwa muma scans ne biopsies. Mushure mekusarudza nzira dzakaoma muzvipatara zvemuno, kusanganisira chemotherapy nekuvhiyiwa, chirwere ichi chakaramba chichikura, nezviratidzo zvekupararira kwemasero emapfupa uye kushanda kwemupfupa kushoma. Vachishuva kubudirira, vabereki vake vakatsvaga kurapwa kwepamusoro-soro kunze kwenyika uye vakawana BIOOCUS, nzvimbo inotungamira mukurapa masero.

KuBIOOCUS, Lev akagamuchira rubatsiro rwemunhu oga kubva pakutanga. Chikwata chedu chekurapa chepasi rose chakapa ongororo yemahara zvichibva pane zvaakanyora pakurapwa kwake, chichitungamira mhuri kuburikidza nenhanho imwe neimwe netsitsi nehunyanzvi. Tichiziva kugona kwekurapa kutsva, takapa GD2 CAR-T cell therapy mushure mekugadziriswa ne fludarabine ne cyclophosphamide. Maitiro acho akanga asina matambudziko, nekuda kwezvipatara zvedu zvemazuva ano nevashandi vedu vakazvipira vakavimbisa kusagadzikana kushoma kumurwere mudiki akadaro. Mushure mekuisirwa mushonga, masero aLev eCAR-T akawedzera zvinobudirira, akasvika padanho rakanaka pazuva rechi10 zvichienda mberi, zvichikonzera kuvandudzika kukuru muhutano hwake. MRI yekutevera yakaratidza kukura kwebundu nekuzvimba, zvichiratidza shanduko huru mukurwa kwake.

Chinosiyanisa BIOOCUS nekuzvipira kwedu kune zvigadzirwa zvemhando yepamusoro uye zvemazuva ano. Kurapa kwedu kweCAR-T kwakanangana nezviratidzo zvakaita seGD2, zvichipa tariro apo kurapwa kwechinyakare kunokundikana. Chikwata chevarwere chakabata zvese zvinodiwa, kubva pakubatsira varwere nevhiza kusvika pekugara pakanaka, zvichiita kuti chiitiko ichi chisave nekushushikana kumhuri dzekunze. Mhuri yaLev inorumbidza rutsigiro rwemitauro yakawanda uye kutarisirwa kwavo nguva dzese kwakaita kuti vanzwe vari kumba.