Mnyamata wolimba mtima wochokera ku Russia akulimbana ndi neuroblastoma

Pali mnyamata wolimba mtima dzina lake Lev Kovalev. Ali ndi zaka 7 zokha, ndipo amachokera ku Russia. N’chifukwa chiyani timamutcha wolimba mtima? Nayi nkhani yake yolimbikitsa.

Lev anapezeka ndi matenda a neuroblastoma zaka ziwiri zapitazo, khansa yovuta yomwe inali itakula ngakhale kuti analandira chithandizo choyamba. Banja lake linasokonezeka kwambiri atamva za kufalikira kwa mafupa ndi mavuto ena omwe amawonetsedwa mu scans ndi biopsies. Pambuyo pa njira zovuta m'zipatala zakomweko, kuphatikizapo chemotherapy ndi opaleshoni, matendawa adapitilirabe kukula, ndi zizindikiro za kufalikira kwa maselo ndi kuchepa kwa ntchito ya mafupa. Pofunitsitsa kupita patsogolo, makolo ake adafunafuna chithandizo chapamwamba kunja ndipo adapeza BIOOCUS, malo otsogola pa chithandizo cha chitetezo chamthupi cha maselo.

Ku BIOOCUS, Lev adalandira chithandizo chapadera kuyambira pachiyambi. Gulu lathu lachipatala lapadziko lonse lapansi linapereka mayeso aulere kutengera zolemba zake zachipatala, kutsogolera banja lonse pa sitepe iliyonse mwachifundo komanso mwaluso. Pozindikira kuthekera kwa njira zatsopano zothandizira, tinapereka chithandizo cha maselo a GD2 CAR-T titalandira chithandizo cha fludarabine ndi cyclophosphamide. Njirayi sinali yophweka, chifukwa cha malo athu apamwamba komanso ogwira ntchito odzipereka omwe adatsimikiza kuti wodwala wachinyamata wotereyu sangamve bwino. Pambuyo popatsidwa mankhwala, maselo a CAR-T a Lev adakula bwino, kufika pamlingo wodabwitsa pofika tsiku la 10 ndi kupitirira apo, zomwe zidapangitsa kuti vuto lake likhale bwino kwambiri. MRI yotsatira idawonetsa kuchepa kwa kukula kwa chotupa ndi kutupa, zomwe zidasintha kwambiri pakulimbana kwake.

Chomwe chimasiyanitsa BIOOCUS ndi kudzipereka kwathu ku ntchito zapamwamba komanso zinthu zamakono. Chithandizo chathu cha CAR-T chimayang'ana kwambiri zizindikiro zinazake monga GD2, zomwe zimatipatsa chiyembekezo pamene chithandizo chachikhalidwe sichili bwino. Gulu lothandizira odwala linayang'anira zinthu zonse, kuyambira chithandizo cha visa mpaka malo ogona abwino, zomwe zinapangitsa kuti mabanja apadziko lonse asamavutike. Banja la Lev limayamikira chithandizo cha zilankhulo zosiyanasiyana komanso chisamaliro cha maola onse chomwe chinawapangitsa kumva kuti ali kunyumba.