Lymphoma Yaikulu ya B-cell Yosagwira Mizere Yambiri (DLBCL)

Bambo X, wodwala wamwamuna, anali ndi matenda a multi-line resistant diffuse large B-cell lymphoma (DLBCL), vuto lomwe limadziwika ndi kukana kwa chotupa ku mitundu yosiyanasiyana ya chithandizo. Atawunika koyamba, Bambo X adadandaula za kupweteka kwambiri m'mimba, zomwe zidapangitsa kuti afufuzenso.

Kafukufuku wokhudza kujambula zithunzi, kuphatikizapo Chithunzi 1, adawonetsa kuti pali chipolopolo chachikulu m'mimba, zomwe zikusonyeza kuti matenda ambiri ayamba. Kupezeka kwa chipolopolo chotere sikunangowonjezera kusasangalala kwa m'mimba kwa a X komanso kudapangitsa kuti adandaule za kupita patsogolo ndi kukwiya kwa lymphoma yake.

Poganizira za kupambana kochepa kwa njira zochiritsira zakale komanso kufunikira kothandiza mwachangu, a X adalembetsedwa mu mayeso azachipatala a chithandizo cha maselo a CD19+22 CAR-T. Atachita zokonzekera zofunika, kuphatikizapo chithandizo chisanachitike, a X adalandira chithandizo cha maselo a CD19+22 CAR-T.

Chodabwitsa n'chakuti, Chithunzi 2, chomwe chinatengedwa miyezi itatu pambuyo poti maselo a CD19+22 CAR-T abwereranso, chinawonetsa kutha kwathunthu kwa m'mimba. Kuyankha kodabwitsa kumeneku ku chithandizo kunasonyeza zotsatira zabwino, ndipo lymphoma inathetsedwa bwino.

Paulendo wake wonse wolandira chithandizo, a X adalandira chithandizo chokwanira kuchokera kwa gulu lachipatala. Izi zinaphatikizapo kuyang'anira bwino matenda ake, kuyang'anira zotsatirapo zake zokhudzana ndi chithandizo, komanso thandizo la maganizo kuti limuthandize kuthana ndi mavuto omwe akukumana nawo chifukwa cholimbana ndi khansa.

Kuphatikiza apo, kupitirira chithandizo chamankhwala, tinapatsa a X ntchito zosiyanasiyana kuti atsimikizire kuti ali ndi thanzi labwino panthawi ya chithandizo chawo. Izi zinaphatikizapo kumukonzera malo ogona abwino, kumupatsa chakudya chopatsa thanzi chogwirizana ndi zosowa zake, kukonza mayendedwe a nthawi yake yokumana ndi anthu komanso zofunikira paulendo, komanso kupereka chithandizo chamaganizo kwa iye ndi banja lake kuti awathandize kudutsa nthawi yovutayi.

Nkhani ya a X ikuwonetsa kuthekera kwa njira zatsopano monga chithandizo cha maselo a CAR-T pothana ndi DLBCL yosagonjetsedwa ndi mizere yambiri. Ikugogomezera kufunika kopitiliza kafukufuku ndi chitukuko m'munda wa khansa kuti apereke chiyembekezo ndi njira zochizira bwino odwala omwe akuvutika ndi khansa monga DLBCL.

Miyezi itatu isanafike komanso itatha kulowetsedwa