Lymphoma Pūtau-B Nui Ātete-maha (DLBCL)

I tae mai a Mr. X, he tūroro tāne, me te mate pukupuku lymphoma nui ātete-maha-raina (DLBCL), he mate uaua e tohuhia ana e te ātete o te pukupuku ki ngā momo maimoatanga maha. I te aromatawai tuatahi, i amuamu a Mr. X mō te mamae nui o te puku, ā, i puta ai he rangahau anō.

I whakaatuhia e ngā rangahau whakaahua, tae atu ki te Pikitia 1, he puranga nui i roto i te kōhao puku, he tohu tēnei mō te nui o te mate kua pā ki a Mr. X. Nā te noho mai o taua puranga, kāore i te mea ko te mamae o te puku o Mr. X anake, engari i ara ake anō hoki ngā āwangawanga mō te haere whakamua me te kaha o tana lymphoma.

I te whakaaro ki te iti o te angitu o ngā momo maimoatanga o mua, me te hiahia nui mō te wawaotanga whai hua, i whakaurua a Mr. X ki tētahi whakamātautau haumanu mō te rongoā pūtau CD19+22 CAR-T. Whai muri i te whai i ngā mahi whakarite e tika ana, tae atu ki te maimoatanga o mua, i whiwhi a Mr. X i te werohanga o ngā pūtau CD19+22 CAR-T.

He mea whakamiharo, i whakaatuhia e te Pikitia 2, i tangohia i ngā marama e toru i muri i te urunga mai o ngā pūtau CD19+22 CAR-T, te ngaronga katoa o te puku. Ko tēnei urupare whakamiharo ki te maimoatanga i tohu i te putanga angitu, me te whakakorenga pai o te lymphoma.

I roto i tana haerenga maimoatanga, i whiwhi a Mr. X i te tiaki whānui me te tautoko mai i te tīma hauora. I roto i tēnei ko te aroturuki tata i tōna āhua, te whakahaere i ngā pānga taha e pā ana ki te maimoatanga, me te tautoko kare ā-roto hei āwhina i a ia ki te aro atu ki ngā wero o te pakanga ki te mate pukupuku.

Hei tāpiritanga, i tua atu i te tiaki hauora, i whakaratohia e mātou he whānuitanga o ngā ratonga ki a Mr. X hei whakarite i tōna oranga whānui i te wā e rongoatia ana. I roto i tēnei ko te whakarite wāhi noho whakamarie mōna, te whakarato kai totika e rite ana ki āna hiahia kai, te whakarite waka mō āna whakaritenga me āna whakaritenga haere, me te tuku tautoko hinengaro mōna me tōna whānau hei āwhina i a rātou ki te whakatere i tēnei wā uaua.

E whakaatu ana te kēhi a Mr. X i te kaha o ngā rongoā auaha pēnei i te rongoā pūtau CAR-T ki te wikitoria i te DLBCL ātete-maha-raina. E whakaatu ana i te hiranga o te rangahau me te whanaketanga tonu i roto i te mara o te oncology hei whakarato i te tumanako me ngā kōwhiringa maimoatanga whai hua mō ngā tūroro e pāngia ana e ngā mate pukupuku uaua ki te rongoā pēnei i te DLBCL.

I mua me te 3 marama i muri i te werohanga