Amakuru
Imbogamizi mu kuvura indwara y’ibihumyo ikwirakwira mu barwayi ba kanseri y’amaraso: Ibisobanuro byatanzwe na ASH 2024
Mu nama ngarukamwaka ya ASH yo mu 2024, Porofeseri Sun Yuqian yasangije ubushakashatsi bwe bw’ingenzi ku ndwara y’ibihumyo (bIFD) ku barwayi bafite kanseri y’amaraso, agaragaza imbogamizi zo gusuzuma no kuvura, ndetse n’ibitekerezo bifatika bishingiye ku bushakashatsi buherutse gukorwa.
Iterambere mu gushyira mu byiciro ibyago bya T-ALL: Ishyirwa mu byiciro rishingiye kuri NGS rigaragaza amatsinda mato afite ibyago byinshi
Ubushakashatsi bushya bwasohotse muri Amaraso inonosora uburyo bwo gushyira mu byiciro ibyago byo kurwara kanseri y’amaraso ya T-cell acute lymphoblastic leukemia (T-ALL) hakoreshejwe uburyo bwo gukurikirana indwara bwa next-generation sequencing (NGS), yongera uburyo bwo guhanura ibyabaye no kumenya amatsinda mato ashobora kungukirwa n’ubuvuzi bwihariye.
Gukemura ibibazo by'igihe kirekire by'ubuvuzi bwa CAR-T: Ibisobanuro bivuye kuri Kanseri y'umwimerere
Ubushakashatsi buherutse gusohoka muri Kanseri y'ibidukikije igaragaza ingorane z'igihe kirekire zo kuvura selile za CAR-T, yibanda ku ngaruka zo kwandura no kurwara kanseri y'inyongera, kandi itanga ingamba zo kunoza umusaruro w'abarwayi.
Iterambere mu by'amasomo | Itsinda ry'abaganga rya Lu Daopei ryasohoye ubushakashatsi butangaje mu kinyamakuru cy'ubwongereza cy'ubuvuzi bw'amaraso
Itsinda ry’abaganga rya Lu Daopei, riyobowe na Dr. Cao Xingyu na Prof. Lu Peihua, ryasohoye inyandiko y’ingenzi y’ubushakashatsi ku buvuzi muri Ikinyamakuru cy'Ubwongereza cy'Ubumenyi bw'amaraso (Ingaruka 5.1). Ubushakashatsi bugamije gusuzuma umutekano n'ubushobozi bwo gutera uturemangingo tw'amaraso mu maraso (allo-HSCT) nyuma yo kuvura CD7 CAR-T ku buryo bwo kuvura kanseri y'amaraso mu maraso ya T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma (R/R T-ALL/T-LBL) idashobora kugaragara.
Inkuru y'umurwayi | Uwarokotse Leukemia Ikomeye ya Myeloid (AML-M2): Imyaka 9 nyuma yo guterwa, Yakira imbaraga z'ibyiringiro no kuvuka bundi bushya
Inkuru ikora ku mutima y'umurwayi wo mu bitaro bya Lu Daopei, igaragaza urugendo rw'umugabo w'imyaka 32 warokotse AML-M2, nyuma yo guterwa uturemangingo tw'umubiri, yizihiza imyaka 9 yo koroherwa, abayeho ubuzima bwuzuye kandi burangwa n'urukundo, ibyiringiro, no kwihangana.
Igipimo cyo kubaho cyarushijeho kuba cyiza hamwe na Bu/Cy+Melphalan na Bu/Cy+Thiotepa Regimens mu gutera uturemangingo twa Haploidentical Stem Selplantation ku ndwara ya Non-Down Syndrome Acute Megakaryoblastic Leukemia (AMKL)
Ubushakashatsi bwatanzwe muri ASH 2024 na Dr. Zhi-Jie Wei n'ikipe ye mu bitaro bya Lu Daopei bwerekanye akamaro k'uburyo bwahinduwe bwa Bu/Cy mu gutera uturemangingo tw'amaraso mu maraso ku barwayi ba Non-Down Syndrome Acute Megakaryoblastic Leukemia (AMKL), bwerekana ko abarwayi bafite ikibazo cy'uburwayi bw'amaraso bushobora kurokoka burundu (CR).
Ibisubizo byiza ku buvuzi bwa CD7 CAR-T mu kuvura Lymphoma ya T-Cell yasubiwemo/isubira inyuma muri ASH 2024
Mu nama ngarukamwaka ya ASH yo mu 2024, Porofeseri Lu Peihua wo mu bitaro bya Lu Daopei yagaragaje ibyavuye mu igerageza ry’icyiciro cya mbere ry’ubuvuzi bwa CD7 CAR-T cell therapy ku ndwara ya lymphoma ya T-cell lymphoma (R/R PTCL) yasubiwemo/isubira inyuma, bigaragaza ko ifite akamaro gakomeye kandi ko umutekano wayo ugenzurwa.
Gutsinda Imbogamizi mu Buvuzi bwa CAR-T ku Kanseri y'amaraso ya T-cell
Nubwo ubuvuzi bwa CAR-T bwahinduye uburyo bwo kuvura kanseri ya B-cell, haracyari imbogamizi zikomeye mu kuvura kanseri ya T-cell. Isuzuma riherutse gukorwa rigaragaza ingorane zo kuvura CAR-T muri kanseri ya T-cell mu maraso ndetse n'ibisubizo bishoboka byo gutsinda izi mbogamizi.
Iterambere mu kuvura abantu bakuru B-ALL mu buryo bwa mbere: Isuzuma ryimbitse ryavuye muri The Lancet Haematology
Isuzuma riherutse gukorwa muri Indwara y'amaraso ya Lancet igaragaza intambwe ikomeye mu kuvura kanseri y’amaraso ya B-cell Acute Lymphoblastic Leukemia (B-ALL) ku rwego rwa mbere, hibandwa ku buryo bwo kuvura bwihariye, uburyo bushya bwo kuvura ubudahangarwa bw’umubiri, no kunoza umusaruro w’abarwayi.
Umungavu yongeye kugira icyizere nyuma yo gupimwa na AML M4a Urugendo rwo kwihangana no gukira
Nyuma yo kurwara kanseri y’imitsi ikabije (AML-M4a) no guterwa uturemangingo tw’umubiri duto, umurwayi ukiri muto abona icyizere, ubuzima bwiza, n’intangiriro nshya, bitewe n’ubwitabire budasanzwe bw’ibitaro bya Lu Daopei.
Iterambere rishya mu kuvura no gusuzuma indwara ya Lymphoma yo mu mitsi yo hagati (PCNSL)
Intambwe iherutse guterwa mu gusuzuma no kuvura indwara ya Primary Central Nevervous System Lymphoma (PCNSL) yatanze icyizere gishya ku barwayi. Isuzuma riherutse gukorwa na Kaminuza ya Stanford rigaragaza akamaro ko gusuzuma hakiri kare n'uburyo bugezweho bwo kuvura, harimo imiti ivura indwara zandurira mu mitsi n'uburyo bwo kuvura bugenewe abarwayi.
Inkuru y'umurwayi: Gutsinda Leukemia Ikomeye ya Myeloid no kongera kuvuka nyuma yo guterwa uturemangingo tw'ingirabuzimafatizo
Umurwayi w'umugabo w'imyaka 34 asangiza urugendo rwe ruteye inkunga rwo kurwanya kanseri y'imitsi ikabije (AML), gukorerwa imiti myinshi igabanya ubukana bw'indwara ya kanseri no guterwa uturemangingo tw'umubiri, no kwizihiza imyaka itatu yo gukira no kongera kugira icyizere.