Imbogamizi mu kuvura indwara y’ibihumyo ikwirakwira mu barwayi ba kanseri y’amaraso: Ibisobanuro byatanzwe na ASH 2024

Mu nama ngarukamwaka ya 66 y’Umuryango w’Abanyamerika w’Ubuvuzi bw’Amazi (ASH) mu 2024, Porofeseri Sun Yuqian wo mu Bitaro by’Abantu bya Kaminuza ya Peking yatanze ubushakashatsi bukomeye ku ndwara y’ibihumyo (bIFD) ku barwayi baterwa uturemangingo tw’amaraso mu maraso (allo-HSCT) mu Bushinwa. Ubu bushakashatsi bwakorewe mu bitaro 12, bwasohotse mu kinyamakuru cyemewe cya Indwara zandura Umuryango w'Abanyamerika,Indwara zandura zo kwa muganga (CID).

Ubushakashatsi, buzwi nka CAESAR 2.0, bwibanze ku bantu bakuru 2.015 bahawe imiti irwanya udukoko kuva muri Mutarama kugeza Ukuboza 2021. Bwagaragaje ko 76.08% by'abarwayi bahawe imiti irwanya udukoko, cyane cyane voriconazole (44.37%) na posaconazole (31.71%). Nubwo iyi miti ikoreshwa cyane, ubushakashatsi bwagaragaje ko indwara y'udukoko (IFD) ikwirakwira buri mwaka ku kigero cya 6.3%, aho impfu nyinshi ziterwa na yo zingana na 48.28%. Candida, Aspergillus, n'izindi fungi zagaragaye ko ari zo ndwara zikomeye zitera ubwandu.

Porofeseri Sun yanavuze ku mbogamizi z’ubuvuzi zijyanye no gusuzuma no kuvura bIFD ku barwayi ba kanseri y’amaraso. Impinduka mu mikorere ya IFD ibaho mu gihe cyo kwirinda indwara ziterwa n’udukoko, ibyo bikaba bigora gusuzuma no kuvura. Kubera ko nta gisobanuro gihamye gihari, igipimo cy’indwara ya bIFD kiratandukanye cyane, kuva kuri 1% kugeza kuri 42%. Iri tandukaniro rituma bigorana gushyiraho ibipimo bihamye byo gusuzuma no kuvura.

Imwe mu mbogamizi zikomeye zagaragajwe na Porofeseri Sun ni uburyo ibintu bishobora gutera bIFD, birimo no kurwara indwara ya kanseri igihe kirekire, gukoresha imiti igabanya ubukana bw’indwara ya steroid, no gukoresha imiti myinshi igabanya ubukana bw’indwara. Byongeye kandi, imiti irwanya udukoko ikoreshwa mu gukumira indwara ishobora kutagaragaza ubwoko bwose bw’indwara zishobora gutera, kandi ubwoko bw’udukoko bushobora kwirinda kumenyekana bitewe n’uko ibizamini byo gusuzuma indwara bigabanuka nka PCR na GM bipimwa.

Porofeseri Sun yashimangiye akamaro ko kuvura indwara ziterwa n’imiti hakiri kare, cyane cyane ku barwayi bafite ibyago byinshi byo kugaragaraho ibimenyetso byo kwandura. Yasabye ko ubuvuzi buterwa n’imiti i ...

Ibyavuye mu bushakashatsi bwa CAESAR 2.0 bigaragaza ko hakenewe ingamba zinoze zo gucunga ibyago bya IFD ku barwayi ba HSCT ndetse no gukenera kwihutisha gusuzuma no gutanga ubufasha hakiri kare. Nk’uko Porofeseri Sun yashoje, nubwo imiti irwanya udukoko ikiriho ikomeje kugira uruhare runini, iterambere ry’imiti mishya n’ibikoresho byo gusuzuma ni ingenzi cyane mu kunoza umusaruro w’umurwayi. Uburyo bushya bwo kuvura, nka Ubudahangarwa bw'umubiri n'imiti mishya irwanya udukoko, bishobora gutanga icyizere gishya ku barwayi barwaye izi ndwara zishobora gushyira ubuzima mu kaga.

Ubu bushakashatsi bw’ingenzi kuri bIFD bugaragaza imbogamizi abaganga bahura nazo mu kuvura indwara z’ibihumyo ku barwayi ba kanseri y’amaraso, kandi bugaragaza ko hakenewe iterambere rihoraho mu ngamba zo kwirinda no kuvura.