Nkhani ya Wodwala: B-ALL Yoopsa Kwambiri, Kusamutsira Bone Marrow Ali ndi Miyezi 9, Patatha Zaka Ziwiri—Chiyambi Chabwino cha Msilikali Wachinyamata
M'miyezi yoyambirira ya moyo wake, Shuo Shuo (dzina lodziwika bwino) anakumana ndi matenda omwe mwana aliyense sayenera kupirira. Ali ndi miyezi inayi yokha, anapezeka ndi matenda oopsa a Acute B Lymphoblastic Leukemia (B-ALL) omwe ali ndi MLL-AF4 gene fusion, imodzi mwa mitundu yovuta komanso yoopsa ya khansa ya m'magazi ya ana.
Matendawa adapezeka atapita kuchipatala chifukwa cha kutsekeka kwa mphuno, komwe mayeso ake a magazi adawonetsa kuchuluka koopsa—kuchuluka kwa maselo oyera m'magazi kukukwera pa 480×10^9/L, hemoglobin pa 72g/L, ndi ma platelet pa 39×10^9/L. Zizindikirozi zikusonyeza vuto lalikulu la magazi, ndipo banja lake, lomwe linali ndi nkhawa kwambiri, nthawi yomweyo linafunafuna chithandizo chapadera ku chipatala cha Yanda Lu Daopei.
Pambuyo pofufuzanso, matenda a Shuo Shuo adatsimikizika kuti ali ndi MLL-AF4 positive B-ALL, mtundu wa khansa ya m'magazi yomwe imawopseza kwambiri makanda. Popeza anali wamng'ono komanso matenda ake anali oopsa, madokotala adalimbikitsa kuti aikidwe maselo oyambira kuti apereke mwayi wabwino wochira.
Dr. Wei Zhijie, Mtsogoleri wa Dipatimenti Yosintha Matenda ku Chipatala cha Yanda Lu Daopei, ndi gulu lake adapanga dongosolo lonse la chithandizo. Mu Meyi 2022, Shuo Shuo adalandira njira ya chemotherapy yomwe idapangitsa kuti achotsedwe kwathunthu. Pambuyo pake, adapatsidwa mankhwala ophatikizana kuti atsimikizire kuti leukemia ikupitirirabe kuthetsedwa. Panthawiyi, gulu lachipatala lidapitiliza kulankhulana ndi banja lake nthawi zonse kuti liziyang'anira bwino matenda ake.
Mu Ogasiti 2022, Shuo Shuo, yemwe tsopano ali ndi chikhululukiro chathunthu, adapatsidwa bwino opaleshoni yochotsa maselo a magazi omwe si ogwirizana ndi omwe adapereka. Njirayi idayenda bwino, ndipo maselo ake oyera amagazi ndi ma platelet adalumikizidwa milungu iwiri yokha ndi masiku asanu ndi awiri atangomuika, motsatana. Kufufuza kwa mafupa komwe kunatsatira kunatsimikizira kuti panalibe maselo oopsa, ndipo adapeza chimerism ya 100% ndi mulingo wa majini a MLL-AF4 wa 0%. Kumuikako kunapambana, ndipo mwayi wa Shuo Shuo wochotsa maselo kwa nthawi yayitali unakula kwambiri.
Komabe, ulendo womuika munthu wina sunali wopanda mavuto. Shuo Shuo anakumana ndi matenda a graft-versus-host (GVHD) komanso matenda osatha omwe anakhudza khungu lake. Gulu lachipatala linasintha mankhwala ake mwachangu, ndipo chifukwa cha chisamaliro chawo chapadera, ziphuphu zinayamba kutha, ndipo thanzi lake lonse linayamba kusintha pang'onopang'ono.
Lero, Shuo Shuo ali ndi zaka ziwiri ndi miyezi itatu atalandira chithandizo cha khansa ya m'magazi. Matenda ake a khansa ya m'magazi akadali bwino, ndipo wafika pachimake chachikulu: kuyamba sukulu ya ana aang'ono! Banja lake lili ndi chiyembekezo pamene akumuwona akukula tsiku lililonse.
Ndi kulimba mtima, kulimba mtima, komanso kusagwedezekaPothandizidwa ndi gulu lake lachipatala, Shuo Shuo ali wokonzeka kulandira tsogolo, wodzaza ndi kumwetulira, kuseka, ndi chisangalalo cha ubwana.