- Kurapa
- Uchapupu
- Neuroblastoma
- Gomarara Rakasimba
- Uchapupu
- TILS
- Kurapa Masero eNK
- Myasthenia Gravis (MG)
- Acute Lymphoblastic Leukemia (B-ALL)
- Systemic Lupus Erythematosus (SLE)
- Chirwere cheAcute Lymphoblastic Leukemia (T-ALL)
- Non Hodgkin Lymphoma (NHL)
- Multiple Myeloma (MM)
- Kuparadzira Lymphom yeB-cell yakakura
- B-lymphocytic Leukemia
- Myeloma
VaA -----Diffuse Large B-cell Lymphoma (DLBCL)
VaA, vanobva kuIndia, vane makore makumi matanhatu nematanhatu ekuberekwa, vakatanga rwendo rwavo rwekurapa muna Kubvumbi 2018. Mushure mekuongororwa kwehuremu muruoko rwavo rweruboshwe, uye kuongororwa kwePET-CT yemuviri wese, kuongororwa kweDiffuse Large B-Cell Lymphoma (DLBCL) kwakaitwa. Izvi zvakaratidza kutanga kwekurapwa kwakasimba kwakanangana nekurwisa chirwere ichi.
Pakutanga, VaA vakazotanga kushandisa mishonga yekurapa yeR-EPOCH katatu, vachizotevera mimwe miviri yakafanana. Iyi mishonga yekurapa yakaramba ichienderera mberi kubva muna Kubvumbi 2018 kusvika Gumiguru 2019, nguva inoonekwa nekutsungirira uye kushinga mukutarisana nematambudziko.
Pasinei nekurapwa kwakaoma, dambudziko rakaonekwa panguva yekuongororwazve kwePET-CT muna Gumiguru 2019, zvichiratidza kusarongeka kwemasero matsva munzvimbo yecalcaneus yekurudyi uye nzvimbo yekumusoro yerudyi. VaA, vasina kuodzwa mwoyo, vakashandisa ruzivo rwekuti BIOOCUS Medical Group ndiyo nzvimbo yepamusoro yeCAR-T pasi rose, vakatsvaga ruzivo rwavo.
Mbudzi 2019 yakaratidza shanduko huru apo VaA vakatanga danho idzva rekurapwa vachitarisirwa nechikwata chedu chekurapa. Ongororo dzakadzama dzakaratidza kuti vaiva neCD19 shoma uye CD22 yakasimba kwazvo, zvichiratidza kuti vaiva negomarara rakawanda. Zvichitevera zvakawanikwa izvi, sarudzo yakaitwa yekuenderera mberi nekurapa neCD19+CD22 CAR-T cell therapy, nzira yemazuva ano yakagadzirira kurwisa gomarara iri rinoramba riripo.
Mushure mekuisirwa mushonga uyu, VaA vakabatwa nechirwere cheCytokine Release Syndrome (CRS) chinogoneka, uye vakapora nekukurumidza mushure mezvo. Pakazosvika Ndira 2020, vakaburitswa muchipatara, vachikurudzirwa nemigumisiro yakanaka kubva muPET-CT scan yazvino inoratidza kuderera kwebundu uye kudzikira kukuru kwekushanda kwemuviri.
Rwendo rwaVaA rwunopa tariro, ruchisimbisa kugona kwekurapa kwepamusoro-soro munyaya dzekenza. Pavanotanga chirongwa chekutevera varwere kwenguva refu, chinangwa chiripo ndechekuchengetedza simba idzva uye kudzivirira kudzoka kwechirwere ichi.
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