Ngā Pūrongo
Ko te Whakaora CAR-T Paionia i roto i te Leukemia Lymphoblastic Whakapeka Pūtau-B e Whakaatu Ana i te Whai Huatanga Kore i Oti
E whakaatu ana tētahi rangahau hou i te whai huatanga whakamiharo o te rongoā pūtau CAR-T ki te rongoā i te mate Leukemia Lymphoblastic Acute pūtau-B (B-ALL). Ko te rangahau, e uru ana ki te mahi tahi me BIOOCUS me te Hōhipera o Lu Daopei, e whakaatu ana i ngā whanaketanga nui, e whakatū ana i te rongoā hei kōwhiringa maimoatanga nui.
Ka hurihia e ngā rongoā pūtau CAR-T auaha te maimoatanga o ngā mate pukupuku pūtau-B
Kei te tūhuratia e ngā kairangahau o te Hōhipera o Lu Daopei me ngā hoa mahi o te ao ngā maimoatanga pūtau CAR-T hou, e tuku ana i te tumanako ki ngā tūroro he mate pukupuku pūtau-B. E whakaatu ana tēnei rangahau i ngā whanaketanga o te hoahoa me te tono, e whakaatu ana i ngā hua whai hua me te pūmanawa mō ngā auahatanga ā muri ake nei.
Te Whai Huatanga Ārai Puku Whakarei ake o ngā Pūtau CD19 CAR-T e Hangai Ana ki te 4-1BB i te Maimoatanga i te B-ALL
E whakaatu ana ngā rangahau haumanu tata nei he pai ake te whai huatanga o ngā pūtau CD19 CAR-T e ahu mai ana i te 4-1BB ki te rongoā i te leukemia lymphoblastic acute o ngā pūtau B kua hoki mai, kua uaua rānei te rongoā (r/r B-ALL) ki te whakataurite ki ngā pūtau CAR-T e ahu mai ana i te CD28.
He Hua Pai te Whakaora CD19 CAR-T Iti-Horopeta a te Hōhipera o Lu Daopei mō ngā Tūroro B-ALL
I whakaatuhia e tētahi rangahau tata nei i te Hōhipera o Lu Daopei te whai huatanga me te haumaru o te rongoā pūtau CD19 CAR-T iti-horopeta ki te rongoā i ngā tūroro B acute lymphoblastic leukemia (B-ALL) uaua, kua hoki anō rānei ki te mate. I whakaatuhia e te rangahau, i uru atu ki te 51 ngā tūroro, he tere whakamīharo te murunga katoa me te iti o ngā pānga taha.
He Rautaki Whakatairanga Hou e Whakapai Ake Ana i te Haumaru me te Whai Huatanga o te Whakaora CAR-T i roto i te Leukemia Pūtau B Whakapeka
Kua whakapuakina e te Hōhipera o Lu Daopei me te Hebei Senlang Biotechnology ngā kitenga whakamīharo mai i tā rāua rangahau tata nei mō te haumaru me te whai huatanga o te rongoā CAR-T mō te mate pukupuku toto pūtau-B whakapeka. E whakaatu ana tēnei mahi tahi i te kaha o ngā hoahoa pūtau CAR-T hou ki te whakarei ake i ngā putanga o ngā tūroro.
E whakaatu ana te Rangahau Hou i te Haumaru me te Whai Huatanga o te Whakaora CAR-T i roto i te Rongoā i ngā Mate Pukupuku Pūtau-B
Kua whakaatuhia e tētahi rangahau hou i arahina e Tākuta Zhi-tao Ying o te Peking University Cancer Hospital te haumaru me te whai huatanga o te rongoā pūtau IM19 CAR-T ki te rongoā i ngā mate pukupuku toto pūtau-B kua hoki mai me ngā mate pukupuku toto uaua. I whakaputaina ki te Te Puka Hainamana mō ngā Tarukino Hou, e ai ki te rangahau 11 o roto i te 12 ngā tūroro i ora katoa me te kore he pānga kino kino, e whakaatu ana i te kaha o te IM19 hei kōwhiringa maimoatanga whai hua mō ngā tūroro he iti noa ngā huarahi kē atu.
Ngā Whakatairanga Hou i roto i ngā Pūtau Kaikōhuru Taiao (NK) Neke atu i te 50 Tau
I roto i ngā tekau tau e rima kua pahure ake nei, kua hurihia e ngā rangahau mō ngā pūtau Kaikōhuru Taiao (NK) tō tātou māramatanga ki te ārai mate ā-roto, ā, kua tukuna mai he huarahi hou hei whakatairanga mō te mate pukupuku me te whakaora huaketo.
Whakangungu ā-tau mō te Whakahaere Toto Haumanu me te Hangarau Whakawhiti i tū ki te Hōhipera o Yanda Ludaopei
I tū angitu te Whakangungu ā-Tau 2024 mō te Whakahaere Toto Haumanu me te Hangarau Whakawhiti Toto i te Tāone o Sanhe i te Hōhipera o Yanda Ludaopei. Ko te whāinga o tēnei huihuinga he whakarei ake i te whakahaere toto haumanu me te haumaru o te whakawhiti toto mā roto i ngā wā whakangungu whānui i tae atu ai neke atu i te 100 ngā tohunga hauora mai i ngā whare hauora maha.
He Huarahi Hou i roto i te Mate Pūnaha Ārai Mate o ngā Tamariki: Ka Whakaora te Maimoatanga Pūtau CAR-T i te Tūroro Lupus
I angitu te rongoā a tētahi rangahau matua i te Hōhipera o te Whare Wānanga o Erlangen i tētahi kōtiro 16-tau te pakeke he mate lupus erythematosus (SLE) kino mā te whakamahi i te rongoā pūtau CAR-T. Koinei te whakamahinga tuatahi o tēnei rongoā mō te lupus tamariki, e tuku ana i te tumanako hou mō ngā tamariki he mate pūnaha ārai mate.
Te Whakapai Ake i te Whai Huatanga o PROTAC: He Rangahau Hou
E whakaatu ana tētahi rangahau hou i roto i te Nature Communications i ngā māramatanga matua ki ngā ara tohu ā-roto e whakarerekē ana i te whai huatanga o te whakapōrearea pūmua kua arotahihia mā te whakamahi i ngā PROTAC. Mā tēnei kitenga ka taea te whakatakoto huarahi mō ngā maimoatanga whai hua ake mō te mate pukupuku me ētahi atu mate.
Te Whakatairanga i te Hauora me te Whakaora: Te Tiaki i ia Rā mō ngā Tūroro Leukemia
Ko te whakarite i tētahi wheako maimoatanga haumaru, whakamarie hoki mō ngā tūroro leukemia me whai wāhi ki te tiaki i ia rā, tae atu ki te akuaku taiao, te akuaku whaiaro, te kai totika, me te whakakori tinana tika. Kei roto i tēnei aratohu ngā tohutohu nui mō te tiaki whai hua o ia rā hei tautoko i te whakaora.
He pai te rongoā a te NS7CAR-T Cell Therapy mō te R/R T-ALL/LBL
E whakaatu ana tētahi rangahau hou i te whai huatanga me te haumaru o te rongoā pūtau NS7CAR-T ki te rongoā i te mate pukupuku toto nui pūtau-T kua hoki mai, kua ātete rānei ki te mate pukupuku toto nui pūtau-T (R/R T-ALL) me te mate pukupuku toto nui pūtau-T (R/R T-LBL). Ka tukuna e tēnei rongoā he tumanako hou mō ngā tūroro e pāngia ana e ēnei momo mate pukupuku kaha.