Junaid----Te mate pukupuku toto-B tino kino (B-ALL)

Mā te whakamātautau haumanu CAR-T i roto i te whakawhitinga wheua piriti, ka kore he mate o ngā tūroro B-ALL uaua ki te BIOOCUS Medical Group.

E rima tau ki muri, he tauira a Junaid i te Whare Wānanga Hauora o Pakitāne, ā, ki tonu i te wawata kia noho hei tākuta. Engari i te marama o Mei 2014, i kitea he mate toto nui tōna, arā, te mate B-lymphocytic leukemia, ā, me whakarērea e ia āna akoranga.

Neke atu i te rua tau ia i rongoatia ki te rohe. I te marama o Hānuere 2018, ka pāngia anō ia e te mamae wheua pūnaha, ā, i whakaatuhia e te whakamātautau hinu wheua kua hoki anō ia ki te mate. Whai muri i te akoranga tuarua o te chemotherapy i te hōhipera o te rohe, kāore i taea e ia te murunga hara, ā, kua haere tonu te mate. Nā te rapu ipurangi me te taunakitanga a ētahi atu tūroro, i whakatau rātou ki te haere mai ki tā mātou pokapū CGT mō te whakamātautau haumanu CART taumata teitei me te BMT.

I te 26 o Poutū-te-rangi 2018, i tae mai a Junaid me tōna whānau ki Haina, ā, i whakaurua rātou ki te tari toto whānui. I whakahaerehia e Tākuta he aromatawai whānui mō Junaid. I whakaatuhia e ngā pūrongo ko te kawenga pahūtanga wheua he teitei ki te 69%, ā, he mate harore pūkahukahu tōna. Whai muri i te maimoatanga tupato, i noho pumau te tūroro. I te 24 o Paenga-whāwhā 2018, i whakatōngia anō a Junaid ki ngā pūtau CD19 me CD22 CAR-T takirua. I muri i ngā wiki e rua, kāore i te nui te maha o ngā pūtau pahūtanga wheua. I hoki mai te menemene ki te whānau o Junaid. I whakaritea kia whiwhi a Junaid i te BMT kia kore ai e mate.

I te 25 o Hune 2018, i whakahaerehia e te Tākuta o te tari BMT te BMT mō Junaid, teina rānei. Ko te kaituku mō Junaid ko tōna teina. I te 6 o Hūrae, i tukuna anō te pūtau take taha o te kaituku ki roto i a Junaid, ā, i muri i ngā rā 17 ka oti te whakawhitinga pūtau toto mā, ā, ka nekehia ia i waho o te wāhanga rere toto laminar. I muri i ngā rā 24, kua tino ōrite te momo hinu wheua o tana wheua ki te momo hinu wheua o te kaituku. He kino te arotake o te pūrongo toenga hinu wheua, kāore he raruraru tōmua e pā ana ki te whakawhitinga. I te 6 o Ākuhata 2018, i tukuna a Junaid i te hōhipera, ā, ka tīmata te aroturukitanga o waho.

Ko te whakahaere toto Hainamana te tautoko pakari a te tūroro. Ko Junaid he momo toto RH-negative, he momo toto onge. I whakaae ia ki te "Lang Fang rare blood type alliance" he koha toto kore utu mō ngā wā maha i a ia e noho ana i te hōhipera. Ki a ia, kāore i te ahua he kore toto, he nui te mihi a Junaid me tōna whānau ki te pokapū o te ao mō te mahi i ēnei mea katoa mā Junaid. I taua wā, i haere tahi ngā kaimahi o te pokapū o te ao me Junaid me tōna whānau mai i tō rātou taenga mai ki tēnei wā, i tautoko i a rātou katoa, ā, i āwhina i te whānau ki te wikitoria i te arai reo.

Mā te whakamātautau haumanu CAR-T ka honoa a BMT ki te hanga i tētahi atu merekara. Ko Junaid te tuarua o ngā tūroro mate pukupuku toto-B-lymphocytic acute i Pakitāne kua hoki mai, ā, he uaua ki te rongoā kia whiwhi i te maimoatanga CAR-T Bridge BMT. Ko te tukunga angitu o Junaid i te hōhipera he tohu anō tēnei i te mōhiotanga o te ao ki te hangarau matatau o tā mātou hōhipera mō te whakawhitinga piriti CAR-T.