Bjørn Simensen ---- Multiple Myeloma (IgG lambda) ISS-II

Barka da warhaka! Majinyaci daga ƙasar Norway, Bjørn Simensen, ya shafe shekaru biyu yana jinya.

Mutumin mai shekaru 67, Bjørn Simensen, ya bayyana a asibiti a watan Satumba na 2017 yana korafin tari da ciwon ƙirji. A lokacin aikin tiyatar, an gano yana da myeloma mai yawa (IgG lambda) ISS-II. An ba wa majinyacin maganin bortezomib, lenalidomide da dexamethasone chemotherapy sau 4. Bayan zagayowar 4, furotin M ɗinsa bai kai 1g/l ba. An ba majinyacin kulawar lenalidomide (10mg qdx3 makonni a kowane wata) wanda ya ci gaba har tsawon shekaru 2 masu zuwa. Ya kasance ba shi da cututtuka har zuwa bazara na 2021 lokacin da aka gano yana da yawan furotin M (5g/l). An dakatar da Lenalidomide kuma an fara shan carfilzomib da daratumumab chemotherapy daga Oktoba zuwa Disamba 2021. Duk da haka, chemotherapy bai yi tasiri ba kuma BM MRD bayan chemotherapy ya nuna yana da kyau.

An fara ganin Mr Bjørn Simensen a cibiyarmu ta CGT a ranar 14 ga Fabrairu, 2022. Gwajin BM MRD nasa ya nuna kashi 0.25 cikin 100 na ƙwayoyin plasma marasa kyau. IEF ya nuna cewa furotin IgG da M suna da 3 g/l. PET-CT Scan ya nuna ƙaruwar shan ƙwayoyi a cikin ƙwai musamman wanda ya dace wanda aka ƙara girmansa bayan an yi gwaji. An yi gwajin biopsy na ƙwai wanda ya nuna ƙwayoyin plasma masu cutarwa. An zaɓi majiyyacin don maganin ƙwayoyin CART. An yi amfani da fludarabine da cyclophosphamide na tsawon kwanaki 3. An saka ƙwayoyin CAR-T a rana ta 0 (4/3/2222). Adadin da aka bayar shine 0.5X10^6 /kg. Bayan allurar, majiyyacin ya kamu da zazzabin neutropenia wanda aka sarrafa shi da maganin rigakafi. Kumburin ƙwai na dama ya ragu a hankali zuwa girman da ya dace. A ranar 28 ga gwajin BM bai nuna ƙwayoyin plasma ba. An sallami majiyyacin daga Lu Daopei tare da bin diddiginsa akai-akai a cibiyar kula da jini a birninsa.