Ciwon huhu na ƙananan ƙwayoyin halitta mai tsanani-01

A watan Yunin 2022, wani majiyyaci namiji mai shekaru 65 ya yi gwajin lafiya na yau da kullun, kuma gwajin CT ya nuna wata ƙulli a ƙarƙashin pleura a saman dama na huhu. A watan Janairun 2023, majiyyacin ya fara fuskantar alamu kamar surutu, tari, da kuma ƙarancin numfashi. Zuwa watan Mayun 2023, tari da ƙarancin numfashinsa sun tsananta. An nuna ƙaruwar ayyukan metabolism a cikin ƙulli na huhu na sama na dama, wanda ke nuna alamun cutar kansar huhu. Bugu da ƙari, an lura da ƙaruwar ayyukan metabolism a cikin ƙwayoyin lymph da yawa, ciki har da yankin supraclavicular na dama, mediastinum, trachea, yankin para-aortic, da kuma ƙananan vena cava. Hotunan sun kuma nuna kauri da yawa na nodular a cikin pleura na dama tare da ƙaruwar ayyukan metabolism. Sakamakon gwaji ya nuna metastasis na pleural na dama tare da fitar da pleural, kuma an tabbatar da ganewar ƙarshe na cutar kansar huhu ta ƙananan ƙwayoyin halitta ta hanyar binciken cututtuka, hoto, da immunohistochemistry. Daga nan majiyyacin ya sami magani sosai.

Bayan watanni biyar, ƙarar ciwon ya ragu sosai, kuma yawancin raunukan da suka faru a lokacin da aka yi tiyatar sun ɓace. Tsarin maganin ya haɗa da maganin rigakafi na farko na atezolizumab tare da maganin da aka yi niyya ga anlotinib. An ba da Atezolizumab a kashi na 1200 MG a rana ta farko, sannan aka dakatar da magani. An ba da Anlotinib ta baki a kashi na 10 MG kowace rana na tsawon makonni biyu a jere, sannan aka sake yin hutu na kwanaki bakwai, wanda hakan ya samar da zagayowar magani na kwanaki 21. Bayan zaman jiyya na kwanaki 15, hotunan CT sun nuna raguwar raunin da ya faru a cikin huhun dama, kuma mediastinum da lymph na dama suma sun ragu sosai. Wani hoton CT da aka yi a ranar 10 ga Satumba, 2023, ya nuna canje-canje masu kyau: raguwar fitar da pleural na dama, raguwar kauri na pleural na dama, da ƙananan ƙwayoyin lymph na mediastinal da na dama, ba tare da faɗaɗa ƙwayoyin lymph na ciki da na retroperitoneal ba.

Idan aka kwatanta da hoton da aka ɗauka a ranar 7 ga Mayu, 2023, hoton da aka ɗauka a ranar 10 ga Oktoba, 2023, ya nuna raguwar ƙari sosai. Musamman ma, an lura da raguwar ƙashi a cikin ƙugu a saman lobe na dama da kuma a cikin ƙwayoyin lymph da dama kusa da trachea, jijiyoyin jini, yankin para-aortic, da kuma ƙananan vena cava. Kauri da aka gani a baya a cikin peritoneum na gida, bangon ƙirji na gaba na dama, da kuma sararin intercostal na 11-12 ya ragu sosai. Bugu da ƙari, inuwar nodular mai ƙarancin yawa a cikin tsokar kafada ta dama shi ma ya ragu sosai. Waɗannan sakamakon sun nuna cewa tsarin maganin ya yi tasiri, inda yawancin raunukan da suka faru a lokacin da aka yi tiyatar suka ɓace kuma sauran raunukan suka ragu sosai. Kimanta hotuna sun nuna cewa tsarin maganin ya yi nasara, kuma ciwon yanzu yana cikin wani mataki na gyarawa kaɗan.